Rock Band 3 – очередной музыкальный проект от Harmonix. Сохранена классическая система управления. Главной целью геймеров по-прежнему станет попадание в «игровые ноты». Вы сможете попробовать себя в роли гитариста, бас-гитариста, барабанщика, клавишника и солиста.
Появился pro-режим, в котором можно играть только на pro-гитарах. У такой миди-гитары 102 кнопки(!) и шесть струн.
А также появилась возможность подключать сразу три микрофона.

Таблица совместимости игрового оборудования с Rock Band 3:

ГИТАРЫ	XBOX 360	PS3	Wii
ROCK BAND 3 SQUIER	да	да	да
ROCK BAND 3 MUSTANG	да	да	да
THE BEATLES: ROCK BAND HOFNER BASS	да	да	да
THE BEATLES: ROCK BAND GRETSCH DUO JET	да	да	да
THE BEATLES: ROCK BAND RICKENBACKER 325	да	да	да
ROCK BAND 2 STRATOCASTER	да	да	да
ROCK BAND STRATOCASTER	да	да	да
GUITAR HERO WARRIORS OF ROCK GUITAR	да	да	да
GUITAR HERO 5 GUITAR	да	да	да
GUITAR HERO WORLD TOUR GUITAR	да	да	да
GUITAR HERO 3 LES PAUL	да	да	да
GUITAR HERO 2 X-PLORER	да	нет	нет
BAND HERO GUITAR	да	да	да
MAD CATZ TELECASTER	да	нет	нет
MAD CATZ PRECISION BASS	да	да	да
БАРАБАНЫ	XBOX 360	PS3	Wii
THE BEATLES: ROCK BAND LUDWIG DRUMS	да	да	да
ROCK BAND 2 DRUMS	да	да	да
ROCK BAND DRUMS	да	да	да
GUITAR HERO WARRIORS OF ROCK DRUMS	да	да	да
GUITAR HERO WORLD TOUR DRUMS	да	да	да
BAND HERO DRUMS	да	да	да
ROCK REVOLUTION DRUMS	да	да	нет
ION DRUMS	да	да	да
МИКРОФОНЫ	XBOX 360	PS3	Wii
THE BEATLES: ROCK BAND MICROPHONE	да	да	да
ROCK BAND 2 MICROPHONE	да	да	да
ROCK BAND MICROPHONE	да	да	да
GUITAR HERO WORLD TOUR MICROPHONE	да	да	да
BAND HERO MICROPHONE	да	да	да
LIPS WIRELESS MICROPHONE	да	нет	нет
SINGSTAR WIRED & WIRELESS MICROPHONE	нет	да	нет
MAD CATZ CONTROLLER MICROPHONE	да	нет	нет
PDP MICROPHONE	да	да	нет
КЛАВИШНЫЕ	XBOX 360	PS3	Wii
ROCK BAND 3 KEYBOARD	да	да	да

Всего в Rock Band 3, войдет 83 музыкальных композиции:

1. Amy Winehouse – "Rehab"
2. Antrax – "Caught in a Mosh"
3. At The Drive-In – "One Armed Scissor"
4. Avenged Sevenfold – "Beast And The Harlot"
5. The B-52s – "Rock Lobster"
6. The Beach Boys – "Good Vibrations" (Live)
7. Big Country – "In a Big Country"
8. Blondie – "Heart of Glass"
9. Bob Marley & The Wailers – "Get Up, Stand Up"
10. The Bronx – "False Alarm"
11. Chicago – "25 or 6 to 4"
12. The Cure – "Just Like Heaven"
13. David Bowie – "Space Oddity"
14. Deep Purple – "Smoke on the Water"
15. Def Leppard – "Foolin'"
16. Divo – "Whip It"
17. Dio – "Rainbow in the Dark"
18. Dire Straights – "Walk of Life"
19. The Doobie Brothers – "China Grove"
20. The Doors – "Break On Through (To the Other Side)"
21. Dover – "King George"
22. Echo & the Bunnymen – "The Killing Moon"
23. Elton John – "Saturday Night's Alright for Fighting"
24. Faith No More – "Midlife Crisis"
25. Filter – "Hey Man, Nice Shot"
26. The Flaming Lips – "Yoshimi Battles the Pink Robots, Pt. 1"
27. Foreigner – "Cold as Ice"
28. Golden Earring – "Radar Love"
29. HIM – "Killing Loneliness"
30. Huey Lewis and the News – "The Power of Love"
31. Hypernova – "Viva La Resistance"
32. Ida Maria – "Oh My God"
33. INXS – "Need You Tonight"
34. The J. Geils Band – "Centerfold"
35. James Brown – "I Got You (I Feel Good)"
36. Jane's Addiction – "Been Caught Stealing"
37. The Jimi Hendrix Experience ˆ"Crosstown Traffic"
38. Joan Jett and the Blackhearts – "I Love Rock 'n Roll"
39. John Lennon – "Imagine"
40. Juanes – "Me Enamora"
41. Lynyrd Skynyrd – "Free Bird"
42. Maná – "Oye Mi Amor"
43. Marilyn Manson – "The Beautiful People"
44. Metric – "Combat Baby"
45. The Muffs – "Outer Space"
46. Night Ranger – "Sister Christian"
47. Ozzy Osbourne – "Crazy Train"
48. Paramore – "Misery Business"
49. Phish – "Llama"
50. Phoenix – "Lasso"
51. The Police – "Don't Stand So Close to Me"
52. Poni Hoax – "Antibodies"
53. Pretty Girls Make Graves – "Something Bigger, Something Brighter"
54. Primus – "Jerry Was a Race Car Driver"
55. Queen – "Bohemian Rhapsody"
56. Queens of the Stone Age – "No One Knows"
57. Rammstein – "Du Hast"
58. Ramones – "I Wanna Be Sedated"
59. Raveonettes – "Last Dance"
60. Rilo Kiley – "Portions for Foxes"
61. Riverboat Gamblers – "Don't Bury Me... I'm Still Not Dead"
62. Roxette – "The Look"
63. Slipknot – "Before I Forget"
64. Smash Mouth – "Walkin' on the Sun"
65. The Smiths – "Stop Me If You've Heard This One Before"
66. The Sounds – "Living in America"
67. Spacehog – "In the Meantime"
68. Steve Miller Band – "Fly Like an Eagle"
69. Stone Temple Pilots – "Plush"
70. Swingin' Utters – "This Bastard's Life"
71. T. Rex – "20th Century Boy"
72. Tears for Fears – "Everybody Wants to Rule the World"
73. Tegan and Sara – "The Con"
74. Them Crooked Vultures – "Dead End Friends"
75. Tokio Hotel – "Humanoid"
76. Tom Petty and The Heartbreakers - "I Need to Know"
77. The Vines – "Get Free"
78. War – "Low Rider"
79. Warren Zevon – "Werewolves of London"
80. The White Stripes – "The Hardest Button to Button"
81. Whitesnake – "Here I Go Again"
82. The Who – "I Can See for Miles"
83. Yes – "Roundabout".